human tm Search Results


recombinant kim 1 protein  (R&D Systems)
94
R&D Systems recombinant kim 1 protein
Recombinant Kim 1 Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/Recombinant+Human+TIM-1%2FKIM-1%2FHAVCR+His-tag+Protein%2C+CF/pmc04178434-179-33-42
Average 94 stars, based on 1 article reviews
recombinant kim 1 protein - by Bioz Stars, 2026-09
94/100 stars
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rhtim 4 fc  (R&D Systems)
93
R&D Systems rhtim 4 fc
Rhtim 4 Fc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/Recombinant+Human+TIM-4+Fc+Chimera+Protein%2C+CF/bio_rxiv__64898__2025__12__22__696083-230-17-18
Average 93 stars, based on 1 article reviews
rhtim 4 fc - by Bioz Stars, 2026-09
93/100 stars
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tlr4 md 2 complex  (R&D Systems)
93
R&D Systems tlr4 md 2 complex
Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) <t>TLR4</t> signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.
Tlr4 Md 2 Complex, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/Recombinant+Human+TLR4%2FMD2+Complex+Protein/pm36220391-158-1-7
Average 93 stars, based on 1 article reviews
tlr4 md 2 complex - by Bioz Stars, 2026-09
93/100 stars
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cd141  (Miltenyi Biotec)
94
Miltenyi Biotec cd141
Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) <t>TLR4</t> signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.
Cd141, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/CD141+(BDCA-3)+Antibody%2C+anti-human/pmc03747821-66-71-74
Average 94 stars, based on 1 article reviews
cd141 - by Bioz Stars, 2026-09
94/100 stars
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timp 2  (R&D Systems)
91
R&D Systems timp 2
Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) <t>TLR4</t> signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.
Timp 2, supplied by R&D Systems, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/Recombinant+Human+TIMP-2+Protein%2C+CF/pm37456058-71-0-8
Average 91 stars, based on 1 article reviews
timp 2 - by Bioz Stars, 2026-09
91/100 stars
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recombinant timp 3  (R&D Systems)
94
R&D Systems recombinant timp 3
Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) <t>TLR4</t> signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.
Recombinant Timp 3, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/Recombinant+Human+TIMP-3+Protein%2C+CF/10__1074_slash_jbc__m112__371153-70-0-6
Average 94 stars, based on 1 article reviews
recombinant timp 3 - by Bioz Stars, 2026-09
94/100 stars
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tlr4 md2  (R&D Systems)
93
R&D Systems tlr4 md2
Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) <t>TLR4</t> signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.
Tlr4 Md2, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/Recombinant+Human+TLR4%2FMD-2+Complex+Protein%2C+CF/pmc11847140-64-7-8
Average 93 stars, based on 1 article reviews
tlr4 md2 - by Bioz Stars, 2026-09
93/100 stars
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mcl 1  (OriGene)
90
OriGene mcl 1
Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) <t>TLR4</t> signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.
Mcl 1, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/MCL1+(NM_001197320)+Human+Tagged+ORF+Clone+Lentiviral+Particle/pm31384313-77-6-19
Average 90 stars, based on 1 article reviews
mcl 1 - by Bioz Stars, 2026-09
90/100 stars
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recombinant tim 3  (R&D Systems)
94
R&D Systems recombinant tim 3
Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) <t>TLR4</t> signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.
Recombinant Tim 3, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/Recombinant+Human+TIM-3+Fc+Chimera+Protein%2C+CF/pmc05617401-151-8-11
Average 94 stars, based on 1 article reviews
recombinant tim 3 - by Bioz Stars, 2026-09
94/100 stars
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human tm elisa kit  (Elabscience Biotechnology)
93
Elabscience Biotechnology human tm elisa kit
Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) <t>TLR4</t> signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.
Human Tm Elisa Kit, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/Human+TM+(Thrombomodulin)+ELISA+Kit/pmc10813863-114-11-20
Average 93 stars, based on 1 article reviews
human tm elisa kit - by Bioz Stars, 2026-09
93/100 stars
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human tim 4 his tag protein  (R&D Systems)
94
R&D Systems human tim 4 his tag protein
Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) <t>TLR4</t> signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.
Human Tim 4 His Tag Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/Recombinant+Human+TIM-4+His-tag+Protein%2C+CF/pm37194236-435-15-20
Average 94 stars, based on 1 article reviews
human tim 4 his tag protein - by Bioz Stars, 2026-09
94/100 stars
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bcl2 family member mcl1  (OriGene)
93
OriGene bcl2 family member mcl1
Figure 5. Effects of Tan and Im on BCR/ABL signaling and apoptosis‑regulatory proteins in Philadelphia chromosome‑positive acute lymphoblastic leukemia. SUP‑B15 cells were treated with 0.1% DMSO (control), 2 µM Im, 4 µM Tan or the combination of 2 µM Im and 4 µM Tan for 24 and 48 h. SUP‑B15/RI cells were treated with 0.1% DMSO (control), 10 µM Im, 8 µM Tan or the combination of 10 µM Im and 8 µM Tan for 24 h and 48 h. At the end of the treatments, the cells were collected, and the total proteins were extracted for western blot analysis using the corresponding antibodies. One representative western blot is presented. GAPDH was used as the loading control. (A) Effects of Tan and Im on the activation of BCR/ABL, STAT5 and MEK in SUP‑B15 cells. (B) Effects of Tan and Im on the activation of BCR/ABL, STAT5 and MEK in SUP‑B15/RI cells. (C) Effects of Tan and Im on the anti‑apoptotic proteins <t>BCL2</t> and <t>MCL1</t> in SUP‑B15. (D) Effects of Tan and Im on the anti‑apoptotic proteins BCL2 and MCL1 in SUP‑B15/RI. Im, imatinib; MCL1, MCL1 apoptosis regulator, BCL2 family member; p‑, phosphorylated; Tan, tanshinone IIA.
Bcl2 Family Member Mcl1, supplied by OriGene, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+tm/MCL1+(NM_021960)+Human+Tagged+ORF+Clone/pm34820006-56-6-13
Average 93 stars, based on 1 article reviews
bcl2 family member mcl1 - by Bioz Stars, 2026-09
93/100 stars
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Image Search Results


Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) TLR4 signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.

Journal: The Journal of biological chemistry

Article Title: DNA-mediated proteolysis by neutrophil elastase enhances binding activities of the HMGB1 protein.

doi: 10.1016/j.jbc.2022.102577

Figure Lengend Snippet: Figure 6. Potential roles of the DNA-mediated proteolytic processing of HMGB1 by neutrophil elastase in NETs. Due to the enhanced binding activities of the processed HMGB1 protein, this processing may promote (1) TLR4 signaling, (2) binding to biofilm DNA, and (3) DNA sensing by cGAS. Due to the loss of residues 177–215, the processing of HMGB1 may diminish (4) RAGE signaling and (5) nuclear localization. NET, neutrophil extracellular trap.

Article Snippet: Lyophilized TLR4 MD-2 complex was purchased from R&D Systems (catalog no.: #3146-TM-050).

Techniques: Binding Assay

Figure 5. Effects of Tan and Im on BCR/ABL signaling and apoptosis‑regulatory proteins in Philadelphia chromosome‑positive acute lymphoblastic leukemia. SUP‑B15 cells were treated with 0.1% DMSO (control), 2 µM Im, 4 µM Tan or the combination of 2 µM Im and 4 µM Tan for 24 and 48 h. SUP‑B15/RI cells were treated with 0.1% DMSO (control), 10 µM Im, 8 µM Tan or the combination of 10 µM Im and 8 µM Tan for 24 h and 48 h. At the end of the treatments, the cells were collected, and the total proteins were extracted for western blot analysis using the corresponding antibodies. One representative western blot is presented. GAPDH was used as the loading control. (A) Effects of Tan and Im on the activation of BCR/ABL, STAT5 and MEK in SUP‑B15 cells. (B) Effects of Tan and Im on the activation of BCR/ABL, STAT5 and MEK in SUP‑B15/RI cells. (C) Effects of Tan and Im on the anti‑apoptotic proteins BCL2 and MCL1 in SUP‑B15. (D) Effects of Tan and Im on the anti‑apoptotic proteins BCL2 and MCL1 in SUP‑B15/RI. Im, imatinib; MCL1, MCL1 apoptosis regulator, BCL2 family member; p‑, phosphorylated; Tan, tanshinone IIA.

Journal: Oncology letters

Article Title: Tanshinone IIA potentiates the efficacy of imatinib by regulating the AKT-MDM2-P53 signaling pathway in Philadelphia chromosome-positive acute lymphoblastic leukemia.

doi: 10.3892/ol.2021.13125

Figure Lengend Snippet: Figure 5. Effects of Tan and Im on BCR/ABL signaling and apoptosis‑regulatory proteins in Philadelphia chromosome‑positive acute lymphoblastic leukemia. SUP‑B15 cells were treated with 0.1% DMSO (control), 2 µM Im, 4 µM Tan or the combination of 2 µM Im and 4 µM Tan for 24 and 48 h. SUP‑B15/RI cells were treated with 0.1% DMSO (control), 10 µM Im, 8 µM Tan or the combination of 10 µM Im and 8 µM Tan for 24 h and 48 h. At the end of the treatments, the cells were collected, and the total proteins were extracted for western blot analysis using the corresponding antibodies. One representative western blot is presented. GAPDH was used as the loading control. (A) Effects of Tan and Im on the activation of BCR/ABL, STAT5 and MEK in SUP‑B15 cells. (B) Effects of Tan and Im on the activation of BCR/ABL, STAT5 and MEK in SUP‑B15/RI cells. (C) Effects of Tan and Im on the anti‑apoptotic proteins BCL2 and MCL1 in SUP‑B15. (D) Effects of Tan and Im on the anti‑apoptotic proteins BCL2 and MCL1 in SUP‑B15/RI. Im, imatinib; MCL1, MCL1 apoptosis regulator, BCL2 family member; p‑, phosphorylated; Tan, tanshinone IIA.

Article Snippet: The antibody against MCL1 apoptosis regulator, BCL2 family member (MCL1) was purchased from OriGene Technologies, Inc.

Techniques: Control, Western Blot, Activation Assay